Glycans in Diseases and Therapeutics (Biology of Extracellular Matrix)
Publisher: Springer | ISBN 10: 3642168329 | 2011 | PDF | 199 pages | 2 MB
Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions. This volume of the series SBiology of Extracellular Matrix reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology.