Provides comprehensive coverage of the types of reductions undergone by the various classes of organic chemistry. Discusses reductions according to what bond or functional group is reduced by different reagents. Gives special attention to selective reductions that are suitable for the reduction of one particular type of bond or function without affecting other bonds or functions present in the same molecule.

Provides comprehensive coverage of the types of reductions undergone by the various classes of organic chemistry. Discusses reductions according to what bond or functional group is reduced by different reagents. Gives special attention to selective reductions that are suitable for the reduction of one particular type of bond or function without affecting other bonds or functions present in the same molecule. Special emphasis is placed on enantioselective and diastereoselective reductions effected both by chiral reagents and by microorganisms. Reducing agents are correlated with both the starting compounds and the products of reduction. Includes discussions of methods, mechanisms, stereochemistry, and scopes of reducing agents. Selected laboratory procedures demonstrate the main reduction techniques. Correlation tables and thorough author and subject indexes make this book easy to use.

This book is the updated and expanded Second Edition of Jacqueline Seyden-Penne's practical guide to selection of reducing reagents in organic synthesis. It is an indispensable working resource for organic synthetic chemists-the only reference focusing exclusively on aluminohydrides and borohydrides and their derivatives. Simple to use, it is organized according to specific reductions so that chemists can more easily match the best reagent to a given transformation. Throughout, Dr. Seyden-Penne emphasizes four crucial categories: compatibility, possibilities for partial reduction, the regio- and stereoselectivity of reductions that are altered or controlled by neighboring groups, and asymmetric reductions.

The exceptionally useful chemical-reducing properties of organosilicon hydrides have been known for more than half a century. Since the early discovery of these properties, interest in the use of organosilicon hydrides for the reduction of organic functional groups has increased steadily and has led to the development of many techniques for their deployment in chemo-, regio-, and stereoselective transformations in organic synthesis.